ball milling asymmetric organocatalysis

    ball milling asymmetric organocatalysis

    Asymmetric organocatalysis in a ball mill Beilstein TV

    In this video the authors present asymmetric organocatalyses performed in a ball mill. Three reaction types are being discussed: enantioselective aldol reactions, asymmetric Michael additions to nitro alkenes and dipeptide formations. In the oratory the ball milling

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    Solvent-Free Asymmetric Organocatalysis in a Ball Mill

    Solvent-Free Asymmetric Organocatalysis in a Ball Mill Article in Angewandte Chemie International Edition 45(41):6924-6 February 2007 with 20 Reads How we measure 'reads'

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    Solvent-Free Asymmetric Organocatalysis in a Ball Mill

    organocatalysis; solvent-free reactions Milling around : Aldol and enantioselective anhydride opening reactions were effected in a ball mill under solvent-free conditions to afford products in high yields and with high enantioselectivities after short reaction times (see scheme).

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    发布:Angewandte Chemie 2006Belen Rodriguez Toni Rantanen Carsten Bolm从属关系: Technische Hochschule关于:Aldol reaction Gas chromatography Ball mill Organocatalysis Coupling constant

    Mechanochemistry assisted asymmetric organocatalysis: A

    Oct 19, 2012  Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach. Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.

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    Cited by: 52

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill

    Oct 20, 2006  Solvent‐Free Asymmetric Organocatalysis in a Ball Mill Solvent‐Free Asymmetric Organocatalysis in a Ball Mill Rodríguez, Belén; Rantanen, Toni; Bolm, Carsten 2006-10-20 00:00:00 Milling around: Aldol and enantioselective anhydride opening reactions were effected in a ball mill under solvent‐free conditions to afford products in high yields and with high enantioselectivities after short

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    发布:Angewandte Chemie 2006Belen Rodriguez Toni Rantanen Carsten Bolm从属关系: Technische Hochschule关于:Aldol reaction Gas chromatography Ball mill Organocatalysis Coupling constant

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill † Belén Rodríguez Dr. Institut für Organische Chemie, Rheinisch‐Westfälische Technische Hochschule Aachen, Landoltweg 1, 52056 Aachen, Germany, (+49) 241‐809‐2391

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    发布:Angewandte Chemie 2006Belen Rodriguez Toni Rantanen Carsten Bolm从属关系: Technische Hochschule关于:Aldol reaction Gas chromatography Ball mill Organocatalysis Coupling constant

    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased. This review highlights the progress in asymmetric

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    Cited by: 52

    N‐Heterocyclic Carbene Acyl Anion Organocatalysis by Ball

    Organocatalysis by Ball-Milling Having a ball: The ability to conduct mechanistically complex N-heterocyclic carbene-catalysed acyl anion chemistry under ball-milling conditions is reported for the first time. This process is exem-plified through applications to intermo-lecular-benzoin, intramolecular-benzoin, intermolecular-Stetter and

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    Author: William I. Nicholson, Alex C. Seastram, Saqib A. Iqbal, Benjamin G. Reed‐Berendt, Louis C. Morrill,

    N‐Heterocyclic Carbene Acyl Anion Organocatalysis by Ball

    Abstract The ability to conduct N‐heterocyclic carbene‐catalysed acyl anion chemistry under ball‐milling conditions is reported for the first time. This process has been exemplified through applica

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    Author: William I. Nicholson, Alex C. Seastram, Saqib A. Iqbal, Benjamin G. Reed‐Berendt, Louis C. Morrill,

    Hot Topic: Organocatalysis - Wiley Online Library

    Nov 12, 2019  A highly diastereo‐ and enantio‐selective method for the asymmetric synthesis of molecules containing helne and stereogenic axes was developed based on organocatalysis. Various compounds bearing both helical and axial stereogenic elements were obtained in excellent enantioselectivities.

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    Hot Topic: BiocatalysisSep 18, 2019Asymmetric Organocatalysis in Aqueous Media - Green Jan 21, 2018Halogen Bonding in Solution: Anion Recognition, Templated Jan 16, 2018Halogen Bonding in Organic Synthesis and Organocatalysis Jul 27, 2016查看更多结果

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill † Belén Rodríguez Dr. Institut für Organische Chemie, Rheinisch‐Westfälische Technische Hochschule Aachen, Landoltweg 1, 52056 Aachen, Germany, (+49) 241‐809‐2391

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    发布:Angewandte Chemie 2006Belen Rodriguez Toni Rantanen Carsten Bolm从属关系: Technische Hochschule关于:Aldol reaction Gas chromatography Ball mill Organocatalysis Coupling constant I

    ball milling asymmetric organocatalysis - Mining

    Jan 28, 2013  Mechanochemistry assisted asymmetric organocatalysis: A . Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of mechanochemical techniques in asymmetric organocatalysis, »More detailed

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    Mechanochemistry-Assisted Asymmetric Organocatalysis: A

    Mechanochemistry-Assisted Asymmetric Organocatalysis: A Sustainable Approach techniques in asymmetric organocatalysis has increased. Carbene Acyl Anion Organocatalysis by Ball‐Milling.

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    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.

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    Solvent-free asymmetric organocatalysis in a ball mill.

    Oct 20, 2006  Solvent-free asymmetric organocatalysis in a ball mill. Rodríguez B(1), Rantanen T, Bolm C. Author information: (1)Institut für Organische Chemie, Rheinisch-Westfälische Technische Hochschule Aachen, Landoltweg 1, 52056 Aachen, Germany.

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    Solvent-Free Asymmetric Anhydride Opening in a Ball Mill

    The mechanochemical technique of ball milling has been applied to the asymmetric opening of meso-anhydrides, mediated by the cinchona alkaloid quinidine. A simple up procedure affords the products, optically active dicarboxylic acid monoesters, in high yields, with up to 64% ee. With most substrates no column chromatography was needed. A range of various alcohols, as well as

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    Efficient Ball Mill Procedure In The Green Asymmetric

    Ball Mill Reactions. Read "solventfree asymmetric organocatalysis in a ball mill" on deepdyve - instant access to the journals you need more efficient ball-mill procedure in the green efficient ball-mill procedure in the green asymmetric aldol reaction organocatalyzed by s.

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    Recent efforts directed to the development of more

    Scheme 18 Asymmetric aldol reaction catalyzed by dipeptides 23 and 24 under ball-milling conditions. In more recent , Hernández and Juaristi reported the asymmetric aldol reaction between ketones and various aromatic aldehydes under solvent-free conditions in a ball mill, with organocatalysis by several ( S )-proline-containing dipeptides.

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    Efficient ball-mill procedure in the ‘green’ asymmetric

    Sep 09, 2011  The organocatalytic activity of (S)-proline-based dipeptides 1ac has been evaluated in the asymmetric aldol reaction between representative ketones with various aromatic aldehydes under solvent-free conditions in a ball mill.In particular, the methyl ester of (S)-proline-(S)-tryptophan, (S,S)-1c, proved to be an efficient organocatalyst, and the aldol reaction proceeded with good chemical

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    Recent applications of mechanochemistry in

    In recent years, sustainable organocatalysis has become a relevant target in asymmetric organic synthesis. Among the most successful strategies to achieve “greener” organocatalyzed processes are (1) the elimination of solvent from reaction media, and (2) the use of alternative activation energies such as solvent-free mechanochemistry in high speed ball mills.

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    Grinding-Assisted Asymmetric Organocatalysis: A Solvent

    Grinding-Assisted Asymmetric Organocatalysis: A Solvent-free Approach to the Formation of Vicinal Quaternary and Tertiary Stereocenters Data in Asian Journal of Organic 1(2) October

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    Solvent-free asymmetric aldol reaction organocatalyzed by

    Solvent-free asymmetric aldol reaction organocatalyzed by (S)-proline-containing thiodipeptides under ball-milling conditions Author links open overlay panel

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    Mechanically Induced Solid-State Generation of Phosphorus

    Solvent-Free Asymmetric Organocatalysis in a Ball Mill. Angewandte Chemie International Edition 2006, 45 (10.1002/anie.v45:41) , 6924-6926. DOI: 10.1002/anie.200602820. Belén Rodríguez, Toni Rantanen, Carsten Bolm. Solvent-Free Asymmetric Organocatalysis in a Ball Mill.

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    Organocatalytic activity of α,α-dipeptide derivatives of

    Reactions carried out under ball-milling conditions were performed in a MM200 RETSCH mill, using 5-mL grinding jars and 2 grinding balls of 7 mm of diameter, both of agate. 11. General procedure for the intermolecular aldol reaction catalyzed by dipeptide 1d under ball milling activation.

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    Grinding-Assisted Asymmetric Organocatalysis: A Solvent

    Grinding-Assisted Asymmetric Organocatalysis: A Solvent-free Approach to the Formation of Vicinal Quaternary and Tertiary Stereocenters Data in Asian Journal of Organic 1(2) October

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    Solvent-free asymmetric aldol reaction organocatalyzed by

    Solvent-free asymmetric aldol reaction organocatalyzed by (S)-proline-containing thiodipeptides under ball-milling conditions Author links open overlay panel

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    Asymmetric organocatalysis in a ball mill - CORE

    Asymmetric organocatalysis in a ball mill . By Carsten Bolm, Eusebio Juaristi and Manuel Jörres. Year: 2013. OAI identifier: oai:publications.rwth-aachen.de:229895 Provided by: Publikationsserver der RWTH Aachen University. Download PDF:

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    Mechanically Induced Solid-State Generation of Phosphorus

    Solvent-Free Asymmetric Organocatalysis in a Ball Mill. Angewandte Chemie International Edition 2006, 45 (10.1002/anie.v45:41) , 6924-6926. DOI: 10.1002/anie.200602820. Belén Rodríguez, Toni Rantanen, Carsten Bolm. Solvent-Free Asymmetric Organocatalysis in a Ball Mill.

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    Solvent-free asymmetric aldol reaction organocatalyzed by

    Jan 07, 2012  An efficient, solvent-free ball-milling protocol for the asymmetric aldol reaction between cyclohexanone and cyclopentanone with various aromatic aldehydes using a novel series of (S)-proline-containing dipeptides and thiodipeptides 1af as organocatalysts is reported.In general, (S)-proline-containing thiodipeptides proved to be better organocatalysts relative to their analogous amides.

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    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.

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    发布:Beilstein Journal of Organic 2012Pankaj Chauhan Swapandeep Singh Chimni关于:Text mining Bioinformatics Mechanochemistry Enantioselective synthesis Organoc

    Asymmetric Aldol Reaction Organocatalyzed by (S)-Proline

    Jan 20, 2011  The organocatalytic activity of the methyl ester of (S)-proline-(S)-phenylalanine, (S,S)-2, in the asymmetric aldol reaction between cyclohexanone and acetone with various aromatic aldehydes under solvent-free conditions in a ball mill has been evaluated. α,α-Dipeptide (S,S)-2 catalyzed the stereoselective formation of the expected aldol products, with higher diastereo- and

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    Thermal Effects in the Organocatalytic Asymmetric Mannich

    The proline-catalyzed direct asymmetric Mannich reaction between cyclohexanone, formaldehyde, and various anilines is thermally accelerated. With only 0.5 mol % of catalyst, Mannich products with up to 98% ee have been obtained after a short period of time in reactions performed under microwave irradiation. In situ reduction of the resulting ketones affords N-aryl amino alcohols in up to 86%

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    Organocatalytic activity of α,α-dipeptide derivatives of

    Reactions carried out under ball-milling conditions were performed in a MM200 RETSCH mill, using 5-mL grinding jars and 2 grinding balls of 7 mm of diameter, both of agate. 11. General procedure for the intermolecular aldol reaction catalyzed by dipeptide 1d under ball milling activation.

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    BJOC - Organocatalysis

    Aug 23, 2012  Organocatalysis describes catalysis with low-molecular-weight organic compounds, in which a metal is not part of the active principle. Organocatalysts donate or remove electrons or protons as their activation mode.

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    Approach of Organocatalysis Techniques towards "Green

    Approach of Organocatalysis Techniques towards "Green " Asymmetric Organocatalysis in a Ball Mill, Angew Chem. Int. Ed., 45, 6924-6926. brief status on approach of organocatalysis

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    ChemInform Abstract: Organocatalytic Solvent-Free Hydrogen

    The organocatalytic activity of two of the α,β-dipeptides was then compared in the solvent-free asymmetric aldol reaction under ball-milling activation in order to establish the influence of a

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    Solvent-Free Enantioselective Organocatalyzed Aldol Reactions

    Keywords:Aldol, enamine, green chemistry, proline, solvent-free, asymmetric organocatalysis. Abstract:The use of proline as catalyst for the aldol process has given a boost to the development of organocatalysis as a research area. Since then, a plethora of organocatalysts of diverse structures have been developed for this and other organic

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    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased. This review highlights the progress in asymmetric organocatalytic reactions assisted by

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    ChemInform Abstract: Organocatalytic Solvent-Free Hydrogen

    The organocatalytic activity of two of the α,β-dipeptides was then compared in the solvent-free asymmetric aldol reaction under ball-milling activation in order to establish the influence of a

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    Thermal Effects in the Organocatalytic Asymmetric Mannich

    The proline-catalyzed direct asymmetric Mannich reaction between cyclohexanone, formaldehyde, and various anilines is thermally accelerated. With only 0.5 mol % of catalyst, Mannich products with up to 98% ee have been obtained after a short period of time in reactions performed under microwave irradiation. In situ reduction of the resulting ketones affords N-aryl amino alcohols in up to 86%

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    Efficient ball-mill procedure in the ‘green’ asymmetric

    demonstrated that the efficiency of the process using High Speed In the field of organocatalysis, the asymmetric aldol reaction has Ball-Milling (H) was superior relative to traditional magnetic been extensively studied in view of the fact that this reaction is one stirring: reaction times were shorter and in general chemical yields, of

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    efficient ball mill procedure in the green asymmetric

    ball milling asymmetric organocatalysis - Mining efficient ball mill procedure in the green asymmetric aldol MOBILE CRUSHER Mobile Crusher Introduction. Mobile crusher also named protable crusher is a new crusher equipment, it provides a

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    Solvent-Free Asymmetric Anhydride Opening in a Ball Mill

    The organocatalytic activity of two of the α,β-dipeptides was then compared in the solvent-free asymmetric aldol reaction under ball-milling activation in order to establish the influence of a

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    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.

    More

    Mechanochemistry assisted asymmetric organocatalysis: A

    Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased. This review highlights the progress in asymmetric organocatalytic reactions assisted by

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    Reacciones asimétricas organocatalizadas en ausencia de

    examples of solvent-free strategies that have converted asymmetric organocatalysis into a more sustainable synthetic methodology. KEYWORDS: Asymmetric organocatalysis, green chemistry, solvent-free reactions, ball-milling Áreas emergentes de la educación Química [Química Verde] 1departamento de Química, centro de investigación y de

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    communication with a ball mill - populareducation.co

    Solvent‐Free Asymmetric Organocatalysis in a Ball Mill. Communication. Solvent-Free Asymmetric Organocatalysis in a Ball Mill and the permission to use his ball-mill equipment in the initial phase of this study. Read More. About ball mill fill level monitoring system development and

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    BJOC - Organocatalysis

    Aug 23, 2012  Organocatalysis describes catalysis with low-molecular-weight organic compounds, in which a metal is not part of the active principle. Organocatalysts donate or remove electrons or protons as their activation mode.

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    Recent Advances in Sustainable Organocatalysis IntechOpen

    The recent advances on green and sustainable organocatalysis are revised in this chapter. An important focus on one of the 12 principles of green chemistry, organocatalysis pursues to reduce energy consumption as well as to optimize the use of different resources, targeting to become a sustainable strategy in organic chemical transformations.

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    Organocatalytic solvent-free hydrogen bonding-mediated

    An efficient, solvent-free protocol for asymmetric Michael additions of α-nitrocyclohexanone to nitroalkenes using thiourea derivatives as hydrogen bonding catalysts has been developed. By performing the organocatalytic reactions in a planetary ball mill, high yields (up

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    Solvent-Free Enantioselective Organocatalyzed Aldol Reactions

    Keywords:Aldol, enamine, green chemistry, proline, solvent-free, asymmetric organocatalysis. Abstract:The use of proline as catalyst for the aldol process has given a boost to the development of organocatalysis as a research area. Since then, a plethora of organocatalysts of diverse structures have been developed for this and other organic

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    Solvent-free asymmetric organocatalysis in a ball mill

    Solvent-free asymmetric organocatalysis in a ball mill By Belen Rodriguez, Toni Rantanen and Carsten Bolm No static citation data No static citation data Cite

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